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Juvéderm and Restylane are two types of dermal fillers available on the market for the treatment of wrinkles. They both contain hyaluronic acid, a substance that has plumping effects for the skin.

While the two fillers share similarities, they also have their differences. Learn more about these, as well as the costs and expected results, so you know which hyaluronic-based dermal filler is best for you.

Comparing Juvéderm and Restylane

Juvéderm and Restylane are both considered noninvasive procedures. This means that no surgery is required for either. They also both use hyaluronic acid to treat wrinkles via volume. Below is more information about each procedure.


Juvéderm is designed to treat wrinkles in adults. Each solution has a gel material made with hyaluronic acid.

There are different types of Juvéderm injections intended for different areas of the face. Some are designed for the mouth area only (including the lips), while others add volume to cheeks. Certain injections are also used for the fine lines that can develop around your nose and mouth.

Juvéderm injections have all evolved into XC formulas. These are made with lidocaine, which helps decrease pain during the injections without the need for a separate topical anesthetic.


Restylane also has hyaluronic acid. Some versions of the product line, such as Restylane Lyft, include lidocaine as well. This type of dermal filler is sometimes used around the eyes, as well as on the back of the hands. It's also used to smooth lines around the mouth, enhance the lips, and add lift and volume to the cheeks.

Who is a good candidate?

It's important to schedule a consultation with your provider before booking either Juvéderm and Restylane injections. They will go over any individual risk factors that could disqualify you from getting these dermal fillers.

Juvéderm candidates

Juvéderm is for adults. You may not be a good candidate if you:

  • are allergic to the key ingredients in these injections, including hyaluronic acid and lidocaine
  • have a history of multiple severe allergies or allergic reactions such as anaphylaxis
  • have a history of excessive scarring or skin pigmentation disorders
  • are taking medications that can prolong bleeding such as aspirin (Bufferin), ibuprofen (Advil), or blood thinners
  • have a history of bleeding disorders

Restylane candidates

Restylane is meant for adults. The reasons why you may not be a good candidate for Juvéderm, listed above, apply to Restylane as well.